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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Biologically synthesized black ginger-selenium nanoparticle induces apoptosis and autophagy of AGS gastric cancer cells by suppressing the PI3K/Akt/mTOR signaling pathway

Fig. 3

Mitochondrial damage induced by KP-SeNPs in AGS cells. A Mitochondrial morphology of AGS cells. The mitochondria showed a normal thread-like shape in the control group and the KP-RE-treated (200 µg/mL) group. The mitochondria showed abnormal lamellar shape or swollen round shape in KP-SeNP-treated (200 µg/mL) cells (yellow arrows). B Percentage of AGS cells with normal or abnormal mitochondrial morphology; n > 20. C–E Fluorescence microscopic images of mitochondrial reactive oxygen species (ROS) and mitochondrial superoxide (Mito-SOX) of KP-SeNPs (200 µg/mL) and KP-RE-treated (200 µg/mL) on AGS cells. The images were quantified by Image J software. ** p < 0.01, ***p < 0.001 compared with control

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Journal of Nanobiotechnology

ISSN: 1477-3155

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