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Table 3 Inhibition effects of candidates evaluated by IC50

From: Fabrication of multifunctional metal–organic frameworks nanoparticles via layer-by-layer self-assembly to efficiently discover PSD95-nNOS uncouplers for stroke treatment

Compounds

Structure

IC50 (mM)

ZL006

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1.805 ± 0.151

Baicalin

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0.104 ± 0.001

Baicalein

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0.144 ± 0.022

Emodin-8-O-β-d-glucopyranoside

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0.505 ± 0.082

Gnetol

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0.492 ± 0.063

Corylifol A

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1.801 ± 0.034

Nitidine chloride

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 > 1.805

Chelerythrine

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 > 1.805

Isorhapontigenin

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 > 1.805

Physcion

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 > 1.805

  1. The data reported represent the means ± SD (n = 3)