Table 2 Overview of TEXs cargos and their biological effects in radiation therapy
From: Tumor-derived small extracellular vesicles: potential roles and mechanism in glioma
Donor cell | Exosomal cargos | Receiving cell | Biological effects | References |
|---|---|---|---|---|
Radiation tolerant GBM cells | AHIF | GBM cells | Regulate migration and angiogenesis related factors Promote cell survival, invasion and radiation tolerant | [85] |
Hypoxic GBM cells | miR-301a | Normoxic GBM cells | Target TCEAL7/Wnt-β-cateenin Promote radiation tolerant | [86] |
GBM cells | circ-METRN | GBM cells | Target miR-4709-3p/GRB14/PDGFRα signal Promote radiation tolerant | [103] |