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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: αvβ3 integrin-specific exosomes engineered with cyclopeptide for targeted delivery of triptolide against malignant melanoma

Fig. 2

Preparation and characterization of Exo, cRGD-Exo, and cRGD-Exo/TP. A Schematic diagram of the construction of cRGD-Exo/TP. B The morphology and size distribution of Exo, cRGD-Exo, and cRGD-Exo/TP detected with TEM and dynamic light scattering, respectively. Scale bar: 100 nm. C The expression of Exo-specific protein markers (CD9, TSG101, and CD63) on Exo and cRGD-Exo/TP by western blotting. D, E The flow cytometry results and cellular MFI of A375 cells incubated with cRGD-Exo (different mass ratios of cRGD to Exo). F DL and EE of cRGD-Exo/TP with different mass ratios of cRGD-Exo to TP. G The drug release profiles of cRGD-Exo/TP in different pH release mediums for 72 h

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Journal of Nanobiotechnology

ISSN: 1477-3155

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