Fig. 6
a The bio-distribution of the preparations in tumor-bearing female BALB/c nude mice, b Fluorescence images of the organs and tumor tissues of the mice treated with different preparations at different times, c FI statistical data of the tumor tissues excised from the mice after being treated with different formulations at 24 h. A: Normal saline, B: DiR solution, C: NLC-DiR, D: PEG-NLC-DiR, E: FA-NLC-DiR, F: E-[c(RGDfK)2]-NLC-DiR, G: E-[c(RGDfK)2]/FA-NLC-DiR. ***p < 0.001 vs NLC-DiR, **p < 0.01 vs NLC-DiR, △p < 0.05 vs PEG-NLC-DiR, ○p < 0.05 vs E-[c(RGDfK)2]-NLC-DiR, ##p < 0.01 vs FA-NLC-DiR. Results are expressed as mean ± SD, n = 3