Fig. 6

hsEVs improved the survival of ADSCs in ischemic muscles. A The survival of ADSCs^Fluc/eGFP primed with PBS, nsEVs and hsEVs was detected by BLI. D-Luciferin potassium salt was injected intraperitoneally. B Quantification of BLI signals. C ADSCs^Fluc/eGFP were injected into ischemic limbs; representative photomicrographs of ischemic GC muscle at Day 7. Scale bars, 100 µm. D Quantification of eGFP⁺ cells in photomicrographs of tissue sections. Data are expressed as the mean ± SEM. (n = 5. ^∗P < 0.05 versus ADSCs; ^∗∗P < 0.01 versus ADSCs.