Fig. 4
Copyright 2021, Theranostics. C Use of Aptamer-Modified Dox-Encapsulated EVs (Apt-Exos-D) for effective drug delivery to target cancer [120]. Copyright 2019, Analytical Chemistry
Aptamers as "chemical antibodies" for penetration and accumulation in tumors for targeted drug delivery. A Schematic diagram of the use of aptamer-PEG-cholesterol coupling to modify siRNA-loaded EVs (EXOApt-siRNA). B Confocal images showing that EXOApt prefers to accumulate in prostate cancer cells [119].