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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Targeted OUM1/PTPRZ1 silencing and synergetic CDT/enhanced chemical therapy toward uveal melanoma based on a dual-modal imaging-guided manganese metal–organic framework nanoparticles

Fig. 6

Cellular uptake of NPs. a TEM images indicate the intracellular distribution of NPs in OCM1a. Arrows: NPs uptaken into the cells. The scale bars in the first row and the second row are 5 μm and 1 μm, respectively. b From up to down, the CLSM images show ICG labeled NPs (red), cytoskeleton stained with FITC fluorescence-phalloidin (green), and cell nuclei stained with DAPI (blue) in OCM1a. The scale bars in the left 5 columns and the right 1 column are 50 μm and 20 μm, respectively. c Cellular uptake of NPs evaluated by flow cytometer. Experiments were repeated for three independent times

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Journal of Nanobiotechnology

ISSN: 1477-3155

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