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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Exosome-like nanovesicles derived from Phellinus linteus inhibit Mical2 expression through cross-kingdom regulation and inhibit ultraviolet-induced skin aging

Fig. 3

RNAs in FELNVs exert anti-aging effects. a Effect of FELNVs, RNA free components (FELNVs + RNase A), and RNA components (FELNVs-RNA) on proliferation in UV-treated HaCaT cells by CCK8 assay. b, c Relative SOD enzyme activity (b) and relative SA-β-Gal levels (c) in UV-treated HaCaT cells with RNA treatment of FELNVs. d Flow diagram to show de novo miRNA sequencing and prediction of novel miRNAs. e Sequences of five novel miRNAs (miR-CM1 to CM5) of FELNVs. f Sequence alignment of miR-CM2 with nucleotide collection (nr/nt) of NCBI. Data are expressed as mean ± SD (*P < 0.05, **P < 0.01)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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