Fig. 7

miR-CM1 encapsulated in artificial exosomes can reduce UV-induced aging in mice. a Schematic of the mouse photoaging model. Treatment groups were separately given drug treatment of miR-Exo and FELNVs to the dorsal skin of mice before UVA irradiation. b Schematic demonstrating miR-CM1 encapsulated in artificial exosomes (EXO mimics) into cells to function. c-e Representative images of H&E staining (c), Masson staining (d), and immunohistochemistry (IHC) (e) of skin tissue from mice. Data statistics for epidermal thickness, collagen ratio and relative IHC staining index are shown on the right. Data are expressed as mean ± SD (*P < 0.05, **P < 0.01)