Fig. 2

The performance of the synthesized AgNRs for miRNA sensing. a A schematic diagram of AgNRs (vs. the bare AgNPs) in reporting and amplifying the signals of the hybridization of miRNAs via the electrooxidation process. b A schematic diagram of AgNR synthesis. c UV–vis spectra and the representative photographs (inset) of the bare AgNPs and the AgNRs in 10 mM PBS. d The hydrodynamic diameter of the bare AgNPs and AgNRs by DLS measurement. The TEM images of the bare AgNPs (e) and AgNRs (f). g CV scans after AgNPs or AgNRs added on the e-miRchip. The control group represents the solvent for nano-reporters (10 mM PBS). h The comparison of the oxidation peak current obtained from (g). N ≥ 3 per group, ****p < 0.0001