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Fig. 10 | Journal of Nanobiotechnology

Fig. 10

From: Carbon dots derived from folic acid attenuates osteoarthritis by protecting chondrocytes through NF-κB/MAPK pathway and reprogramming macrophages

Fig. 10

The crosstalk between macrophages and chondrocytes mediated by CDs. A The mRNA expression of M1 or M2-realted markers was investigated in chondrocyte CM-treated RAW264.7 cells. B The protein expression of iNOS, CD68, Arg1, and CD206 in chondrocyte CM-treated RAW264.7 cells was investigated by immunofluorescence assay. Scar bar: 20 μm. C The concentration of proinflammatory mediators in chondrocyte CM-treated RAW264.7 cells. *p < 0.05; **p < 0.01; ***p < 0.001

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