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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: Carbon dots derived from folic acid attenuates osteoarthritis by protecting chondrocytes through NF-κB/MAPK pathway and reprogramming macrophages

Fig. 4

CDs inhibited IL-1β-induced oxidative stress. A Intracellular ROS in chondrocytes with different treatment. Scar bar: 100 μm. B The elevated level of iNOS and COX-2 in IL-1β-induced chondrocytes was rescued by CDs treatment. C Western blot assay indicated CDs could effectively inhibit iNOS and COX-2 expression. D Immunostaining assay showed the dysregulation of iNOS and COX-2 was rescued by CDs treatment. Scar bar: 20 μm. E The restorative effect of CDs on ATP production in IL-1β-stimulated chondrocytes. *p < 0.05; **p < 0.01; ***p < 0.001

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Journal of Nanobiotechnology

ISSN: 1477-3155

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