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Fig. 8 | Journal of Nanobiotechnology

Fig. 8

From: Carbon dots derived from folic acid attenuates osteoarthritis by protecting chondrocytes through NF-κB/MAPK pathway and reprogramming macrophages

Fig. 8

CDs orchestrated macrophage repolarization in vitro. A The mRNA level of M1 and M2-related markers in RAW264.7 cells with different treatment. B Immunofluorescence staining results indicated CDs incubation could prevent the polarization of macrophages to proinflammatory type. Scar bar: 20 μm. C The induced concentration of proinflammatory factors in LPS-induced RAW264.7 cells was suppressed by CDs treatment. D The protein level of iNOS in RAW264.7 cells under different treatment. E Griess assay was used to evaluate the NO scavenging effects of CDs. *p < 0.05; **p < 0.01; ***p < 0.001

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Journal of Nanobiotechnology

ISSN: 1477-3155

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