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Fig. 9 | Journal of Nanobiotechnology

Fig. 9

From: Carbon dots derived from folic acid attenuates osteoarthritis by protecting chondrocytes through NF-κB/MAPK pathway and reprogramming macrophages

Fig. 9

Macrophage CM and co-culture with chondrocytes. A The mRNA expression of markers involved in extracellular matrix degradation, oxidative stress, and inflammation in chondrocytes with macrophage CM incubation was determined. B Representative markers for cartilage degeneration in macrophage CM-treated chondrocytes was estimated by immunofluorescence assay. Scar bar: 20 μm. C The statistical analysis results of fluorescence intensity. D The concentration of TNF-α and IL-6 in macrophage CM-treated chondrocytes. **p < 0.01; ***p < 0.001

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Journal of Nanobiotechnology

ISSN: 1477-3155

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