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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Photoacoustic mediated multifunctional tumor antigen trapping nanoparticles inhibit the recurrence and metastasis of ovarian cancer by enhancing tumor immunogenicity

Fig. 7

Antigen exposure and antitumor immune response induction in vivo. a Immunofluorescence staining of intratumoral CRT/HMGB1. Scale bar 20 μm. b, c Intratumoral mature DC abundance detected by FCM. d, e Intratumoral activated CD8+ T lymphocytes abundance was detected by FCM. f, g The activation of splenic CD8+ T lymphocytes was detected by FCM. h–k The secretion levels of IL-6, IL-12, TNF-α, and IFN-γ in the serum of mice after 7 days of treatment were detected by ELISA (n = 5)

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