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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Thrombus-specific/responsive biomimetic nanomedicine for spatiotemporal thrombolysis and alleviation of myocardial ischemia/reperfusion injury

Fig. 7

Mechanistic study of PTPN in myocardial infarction treatment by next generation sequencing. a Venn diagram of all genes detected in Ctrl, H2O2 + PBS and H2O2 + PTPN conditions. (n = 3 biologically independent samples). b Volcano map of differentially expressed genes (DEG; adjusted p < 0.05; fold change ≥ 2) between H2O2 + PBS and H2O2 + PTPN groups, red represented up-regulated genes and blue represented down-regulated genes. c Heatmap of DEGs from H2O2 + PBS and H2O2 + PTPN groups. d KEGG enrichment barplot of DEGs between H2O2 + PBS and H2O2 + PTPN groups

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