Fig. 7

In vivo subcutaneous tumor therapies. A The scheme of orthotopic tumor inoculation and dosing regimen (Ce6: 2.5 mg/kg, CS-1: 1 mg/kg, CPCM, CPCCM: 5 mg/kg. laser (L) irradiation: 0.2 W/cm⁻²). B Tumor volumes of MDA-MB-231 tumor-bearing mice in different groups. C The average tumor weights of mice with different treatments (n = 5). D Variation of body weights of tumor-bearing mice with different treatments. E Fluorescence photographs of MDA-MB-231-bearing mice with different treatments. F Images of orthotopic tumors harvested from the mice from mice with different treatments. G H&E and TUNEL staining of tumor sections. Data were shown as mean ± SD, n = 5. ANOVA was used to assess statistical significance. *p < 0.05, **p < 0.01, ***p < 0.001