Fig. 7

Transcriptomic analysis of distant tumor and immune response in vivo. A GO enrichment analyses of DEGs in the PBS vs PDT. B Adaptive antitumor immunity-related DEGs screened based on GO biological process enrichment analysis of distant tumor. C–D Evaluation of CD4 + and CD8 + T cells in distant tumors (n = 4). E Immunofluorescence images of CD4 + and CD8 + T cells in distant tumor tissues. Green and red fluorescence indicate CD4 + T cells and CD8 + T cells, respectively. Scale bars: 50 μm. F–I Expression of DCs (F, G), CD4 + T cells and CD8 + T cells (H, I) in spleen after different treatments detected by flow cytometry in vivo (n = 4)