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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Biomimetic calcium carbonate nanoparticles delivered IL-12 mRNA for targeted glioblastoma sono-immunotherapy by ultrasound-induced necroptosis

Fig. 3

cRGD-CM-CaCO3 NPs-induced necroptosis and DAMPs release. A Fluorescence microscope images of annexin V (green fluorescence)/PI (red fluorescence)-stained GL261 cells. Scale bar, 100 µm. B Release of ATP, HMGB1 and bone marrow-derived dendritic cells (BMDCs) maturation after different treatments. Data are expressed as mean ± SEM (n = 5). **P < 0.01, ***P < 0.001

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