Fig. 11
From: Harnessing bioactive nanomaterials in modulating tumor glycolysis-associated metabolism
© 2021 American Chemical Society
A Illustrated mechanism of ferroptosis-strengthened glycolytic programming and macrophage polarization via iron-based MOF nanoparticles (MIL88B/RSL3). B Confocal images of macrophage (red) and tumor cell (green) in tumor tissues. Arrows point to MIL88B/RSL3-induced phagocytosis of tumor cells by macrophages. C H&E staining of draining lymph node sections, showing the inhibition effect of MIL88B/RSL3 on metastasis. Yellow dashed lines distinguished the area of infiltrating tumor cells (T) from lymphocytes (L). Reproduced with permission [144]. Copyright