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Scheme 1 | Journal of Nanobiotechnology

Scheme 1

From: Intestinal epithelium penetration of liraglutide via cholic acid pre-complexation and zein/rhamnolipids nanocomposite delivery

Scheme 1

Schematic illustration of the nanocomposites (LIRA/CA@Zein/RLs) accelerating LIRA oral absorption by facilitating trans-mucus and trans-epithelial permeability. A The preparation of LIRA/CA@Zein/RLs by self-assembly of zein using anti-solvent precipitation method. B In the gastrointestinal tract, zein, CA, and RLs worked cooperatively: zein slowed down the pepsin and pancreatin degradation; CA could enhance trans-mucus and trans-epithelium efficiency of LIRA when RLs mainly stabilized the NPs and improved transcytosis

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Journal of Nanobiotechnology

ISSN: 1477-3155

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