Fig. 4From: Tenofovir-tethered gold nanoparticles as a novel multifunctional long-acting anti-HIV therapy to overcome deficient drug delivery-: an in vivo proof of concept A Columns A1 and A2 represent fluorescent microscope images (40X) of the Ethidium bromide (EtBr)-stained cells treated with compounds and controls, i Represent Negative control, ii Represent positive control, cells treated with 40 µg/mL Cyclophosphamide, iii Represent cells treated with AuNPs, iv Represent cells treated with AuNP-TNF, and v Represent cells treated with TNF, B/C Box & Whiskers plots of comet assay in PBMCs. B Olive Tail Moment (OTM), C %DNA Damage. The solid line indicates the median for each group. The box edges mark the 25th and 75th percentiles of the observed values, and the T-bars indicate the 10th and 90th percentiles. (*** denotes p≤0.0001, the significant difference is in comparison with the drug control, TNF)Back to article page