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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Protective effect of spore oil-functionalized nano-selenium system on cisplatin-induced nephrotoxicity by regulating oxidative stress-mediated pathways and activating immune response

Fig. 3

A GLSO@SeNPs inhibit CDDP-induced caspase-regulated mitochondrial damage. B MMP and mitochondrial morphology in HK-2 cells. C Quantitative analysis of JC-1 intensity proportion for flow cytometry analysis in (a). D mitochondrial morphology in HK-2 cells. E Activity of caspases 3/9 was evaluated with specific fluorescent substrates. F HK-2 cells were treated with 0.04 μL/mL GLSO@SeNPs with 4 μg/mL CDDP, and then, intracellular protein expression levels of caspase 3/8/10, Bcl-2, Bcl-xL, Bad, Bax, and PARP were analyzed. *P < 0.05, #P < 0.05, ##P < 0.01; ns not significant; one-way ANOVA

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Journal of Nanobiotechnology

ISSN: 1477-3155

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