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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Edible and cation-free kiwi fruit derived vesicles mediated EGFR-targeted siRNA delivery to inhibit multidrug resistant lung cancer

Fig. 3

Characterization of STAT3/EKEVs. A Structure diagram of STAT3/EKEVs. B The particle size distribution and representative TEM images of STAT3/EKEVs, respectively. C STAT3/EKEVs size change over 14 days at 4 ℃. One-way ANOVA. ns not significant. Error bars represent SEM (n = 3). D The detailed structure of STAT3/EKEVs was confirmed using confocal laser scanning microscopy (scale bar: 200 nm). Confocal images of STAT3/EKEVs and STAT3/KEVs in E PC9-GR4-AZD1 cells and F H520 cells, respectively. (scale bar: 10 μm). G Flow cytometry characterization of STAT3/EKEVs and STAT3/KEVs internalization in PC9-GR4-AZD1 cells. H Endosome/lysosome escape profiles of STAT3/EKEVs in PC9-GR4-AZD1 cells (scale bar: 10 μm)

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