Fig. 3

Modeling treatment response to immunotherapy using primary mouse samples. a Schematics of the working flow to validate cytotoxicity of CD8+ T cells in four groups including POCCs/T cells with or without anti-PD1, and Matrigel organoids/T cells with or without anti-PD1. b T cells’ killing results in four different groups. The red color represents the dead cells, the green color represents the T cells, and the blue color represents all the cells from POCCs or Matrigel organoids. c Statistical analysis of T cell’s killing efficiencies in four groups. Scale bar: 150 μm