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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Magnetofection of miR-21 promoted by electromagnetic field and iron oxide nanoparticles via the p38 MAPK pathway contributes to osteogenesis and angiogenesis for intervertebral fusion

Fig. 2

Different transfection efficiencies under various magnetofection conditions. A Fluorescence microscope images showing different transfection efficiencies according to different distant ratios of PEI@IONPs:miRNAs [5, 10, 20, or 30, with or without electromagnetic field (EMF) stimulation]. C Semi-quantifications of mean fluorescence intensity under those various conditions. B, D Transfection efficiency under various treatments [PBS, lipofectamine 2000 (lipo 2000), EMF, PEI@INPs, EMF + PEI@IONPs] and corresponding mean fluorescence intensity. E Relative miRNA expression levels of miR-21 under various treatments (PBS, lipo 2000, EMF, PEI@INPs, EMF + PEI@IONPs). *p < 0.05, **p < 0.01, ***p < 0.001 compared to the PBS group; #p < 0.05, ##p < 0.01 compared to the lipo 2000 group

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