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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: BBB-on-a-chip with integrated micro-TEER for permeability evaluation of multi-functionalized gold nanorods against Alzheimer’s disease

Fig. 3

BBB-oC characterization. A Confocal z-projections of ZO-1 and VE-cadherin between endothelial cells into BBB-oC devices. Scale bar 100 μm. B Permeability assays of fluorescent standard molecules with different molecular sizes into the BBB-oC and control without endothelial barrier (N = 3) **** p < 0.0001 C Equivalent circuit diagram that can be applied to our BBB-oC D Nyquist plot of TEER measurement of BBB-oC before (only hydrogel with astrocytes and pericytes) and after endothelial cell seeding at Day 4, 5, 6 and 7

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