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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Low intensity ultrasound-mediated drug-loaded nanoparticles intravaginal drug delivery: an effective synergistic therapy scheme for treatment of vulvovaginal candidiasis

Fig. 5

Synergistic therapeutic effect of US-mediated AmB-NPs for treatment of VVC in rabbit model. A The timeline of the experimental animal treatment and the schematic illustration of US-mediated nanoparticles therapy in vagina. B Macroscopic observation of vaginal vulva redness, swelling and vaginal secretions on seventh day period after different treatment. C The inflammation score was calculated in different group base on the vulva hyperemia, redness and swelling, mucosal ulceration and white secretion. D Quantitative analysis of fungal colony counts (Log10 CFU/mL) of the vaginal lavage fluid in animals infected with C. albicans on the zero, third, and seventh day post-treatmen. Data represent mean ± standard deviation of initial vaginal fungal burden (n = 5 per group). ***P < 0.001. **P < 0.01

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Journal of Nanobiotechnology

ISSN: 1477-3155

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