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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Hyaluronic acid-FGF2-derived peptide bioconjugates for suppression of FGFR2 and AR simultaneously as an acne antagonist

Fig. 7

HA-P5 inhibited FGFR to reverse the overexpression of YTHDF3 induced by DHT. A Heatmap indicates the expression of m6A-related genes in SZ95 cells treated with HA-P5 and AZD4547 with DHT; B qPCR quantified the expression of YTHDF3 in SZ95 cells treated with HA-P5 and AZD4547 with the presence of DHT. One-way ANOVA was employed for statistical analysis. **** refers to p < 0.0001 compared to the control group, while #### refers to p < 0.0001 compared to the DHT-treated group; C Typical FISH images of the transcription of YTHDF3 in rabbit ears treated with HA-P5 and AZD4547 with the presence of DHT

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