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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Biodegradable nanoplatform upregulates tumor microenvironment acidity for enhanced cancer therapy via synergistic induction of apoptosis, ferroptosis, and anti-angiogenesis

Fig. 5

Viability of A THLE-3, B MCF-7, and C 4T1 cells treated with different samples. D Live/dead staining of MCF-7 cells treated different samples (equivalent TAM: 5 µg/mL). E Flow cytometry analysis for the apoptosis of MCF-7 cells at the different treatments (equivalent FePt: 5 µg/mL). F CLSM observation for the LPO of MCF-7 cells treated with different samples (equivalent FePt: 5 µg/mL). G CLSM observation for mitochondria damage of MCF-7 cells treated with different samples (equivalent FePt: 5 µg/mL). H–I Western blot analysis for the protein expression of Bcl-2, Bax, GPX4, and VEGF-A at different sample treatments (equivalent FePt: 5 µg/mL). For B and C, data are means ± SD. n = 5, *P < 0.05; **P < 0.01; ***P < 0.005; ****P < 0.001

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Journal of Nanobiotechnology

ISSN: 1477-3155

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