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Fig. 15 | Journal of Nanobiotechnology

Fig. 15

From: Accelular nanofibrous bilayer scaffold intrapenetrated with polydopamine network and implemented into a full-thickness wound of a white-pig model affects inflammation and healing process

Fig. 15

Time dependence of mean expression of the HRT unit of pro-inflammatory cytokines TNFα (a), IL1β (b), IL17 (c), MMP9 (f), anti-inflammatory cytokines IL10 (d) and growth factor TGFβ1 (e). Each panel represents a specific time of cytokines expression (1 week–6 months) and implanted material, where a bilayer made of collagen/oxidized cellulose cross-linked with nanofibers coated with polydopamine is Coll/CaOC-N/PDA (orange color panel), a bilayer made of collagen/oxidized cellulose cross-linked with nanofibers is Coll/CaOC-N (green color panel).( The panel of the control group (yellow color panel) is the native porcine skin. Statistical significance (*p < 0.05), (**p < 0.005), (***p < 0.001)

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