Fig. 10

Evaluation of pain condition with low-dose celecoxib and high-dose celecoxib treatment. a Von Frey test and b Hot plate test of WT and CHSY3^−/− mice treated with low-dose celecoxib and high-dose celecoxib for 8 weeks. c, d IHC analysis of CGRP, NUEN, and DAPI of DRG of WT and CHSY3^−/− mice treated with low-dose celecoxib and high-dose celecoxib for 8 weeks. *P < 0.05 compared with the sham group, ^#P < 0.05 compared with the low LSI group, and ^†P < 0.05 compared with the high LSI group