Fig. 4From: In vivo toxicity evaluation of tumor targeted glycol chitosan nanoparticles in healthy mice: repeated high-dose of glycol chitosan nanoparticles potentially induce cardiotoxicityOrgan toxicity after single-/multi-dose of CNPs in healthy mice. A The major organs stained with H&E after single- or multi-dose of 10, 22.5 or 90 mg/kg CNPs. Histological analyses were performed on day 7 after treatments. B Hematological parameters after single- or multi-dose of 10, 22.5 or 90 mg/kg CNPs. Blood samples were collected on day 7 after treatments (n = 5). C Complete cell count results after multi-dose of 10, 22.5 or 90 mg/kg CNPs (n=5)Back to article page