Fig. 1
From: Theranostic applications of selenium nanomedicines against lung cancer
Rational design of different SeNPs for cancer treatments. A The internalized Tf-SeNPs trigger the overproduction of intracellular reactive oxygen species (ROS), thereby activating the p53 and mitogen-activated protein kinase (MAPK) pathways and promoting MCF-7 cell apoptosis [47]. Copyright 2013, Elsevier Ltd. B Internalized FA-SeNPs trigger ROS overproduction and induce apoptosis of HePG2 cells by activating the p53 and MAPK pathways [48]. Copyright 2015, Elsevier Ltd. C After the application of GLP − SeNPs, the p53, MAPK and AKT pathways are activated to promote the apoptosis of U87 cells [49]. Copyright 2014, American Chemical Society. D Schematic diagram of SeNP-induced modulation of γδ T cells [50]. Copyright 2019, Elsevier Ltd