Fig. 7
From: Theranostic applications of selenium nanomedicines against lung cancer
Direct cancer cell-killing activity of SeNPs. A Nonmetallic NPs encapsulated in combination with RT further induce DNA damage, prevent rapid DNA repair, and lead to more apoptosis [191]. Copyright 2020, The Author(s). C PEG-SeNPs induce apoptosis through mitochondria-mediated pathways [111]. Copyright 2019, The Royal Society of Chemistry. B, D ROS-dependent regulation of HIF-1 activity by PHD2 (chitosan-coated Se/DDP nanoparticles [CSP NPs]) [112]. Copyright 2019, Elsevier B.V