Fig. 9
From: Active targeting schemes for nano-drug delivery systems in osteosarcoma therapeutics
Targeting moiety scheme design of nano-drug delivery systems. a Schematic illustration of cancer cell membrane-coated NPs (CCNPs) for OS treatment. Copyright 2022, Small. b Preparation of paclitaxel (PTX)-loaded PLGA nanoparticles with 143B-RAW hybrid membrane coating (PTX-PLGA@[143B-RAW] NPs). Copyright 2022, International Journal of Nanomedicine. c Schematic illustration showing a TPP-PPG@ICG nanocomposite targeting a mitochondrion for synergistic phototherapy with a single laser. d FL-confocal microscopic images of MG63/Dox cells co-treated with MitoTracker and either PPG@ICG or TPP-PPG@ICG are shown. Copyright 2021, Journal of Nanobiotechnology. e Confocal microscopy for NLS-mediated nuclear targeted delivery. NPs successfully accumulated around the nucleus. Copyright 2018, Journal of Biomaterials Science, Polymer Edition. f Schematic representation of EISA of 1Lp or 1Dp to result in intranuclear assemblies. Copyright 2022, Angewandte Chemie International Edition