Fig. 6

Inorganic materials-based intracameral drug delivery systems. A Synthesis of pilocarpine-loaded gelatin-covered MSNs (p/GNs). B Transmission electron microscopic images of the (a) MSNs and (b) gelatin-covered MSNs. Scale bar = 50 nm. (c) Cumulative release of pilocarpine from MSNs without gelatin coating and gelatin-covered MSNs (p/GM-x, x is denoted as mg of gelatin on per mg of MSN). C IOP change of the eyes treated with p/GM-x. GL: glaucomatous eyes before operation; H: hour after the administration; D: day after the administration. Reprodcued from Ref. [168] with permission from the Royal Society of Chemistry