Fig. 7

Dendrimer-based intracameral drug delivery systems. A Schematic representation of the manufacture of gelatin grafted PNIPAAm (gelatin-g-PNIPAAm) and intracameral administration of pilocarpine-loaded gelatin-g-PNIPAAm. Reprinted from Ref. [166] with permission from Elsevier. B Transmission electron microscopic images of PAMAM tethered gelatin-g-PNIPAAm (GxG-PN) (x is denoted as the percentages of amino groups in gelatin samples). C Representative slit-lamp biomicroscopic images of rabbit eyes at day 1 and 84 after intracameral injection of GxG-PN thermogels. Scale bars = 5 mm. D The encapsulation efficiency of GxG-PN (a) and cumulative release percentage of pilocarpine from GxG-PN (b). (B)—(D): Reprodcued from Ref. [167] with permission from WILEY–VCH Verlag GmbH and Co. KGaA, Weinheim