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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Combination therapy based on dual-target biomimetic nano-delivery system for overcoming cisplatin resistance in hepatocellular carcinoma

Fig. 2

Schematic diagram of A54-RBCm@NLS-Ag-MOF/DDP/NOR1shRNA (AR-NADR) construction and its combination therapeutic mechanisms in the treatment of cisplatin resistance in HCC by interfering with NOR1. 1 A54 receptor-mediated endocytosis. 2 Immune escape. 3 NLS mediated enter into the cell nucleus. 4 Drug release. 5 Chemotherapy. 6 Downregulation of NOR1. 7 Reduced drug efflux

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