Fig. 8
In vitro antitumor effects of AR-NADR. A Cell viability of HepG2 cells and B HepG2/DDP cells after 24 h treatment with different concentrations of AR-NA, AR-NAR, DDP, AR-NAD and AR-NADR. C The IC50 values of HepG2 cells and HepG2/DDP cells in the DDP, AR-NAD and AR-NADR treated groups. D Live/dead staining of HepG2 cells and HepG2/DDP cells upon various treatments for 6 h. While the living cells displayed green fluorescence, the dead cells exhibited red fluorescence. Scale bar: 100 μm. Data are presented as the means ± SD (n = 3) (ns represents no significance, intergroup comparisons: ***p < 0.001, ****p < 0.0001)