Fig. 7

Intratumoral immune components analysis. A CRT and IDO1 expression and analysis in tumor sections by ICH staining. Scale bar = 100 μm. B Kyn/Trp ratio in tumors by HPLC. C In vivo analysis of tumor infiltrating dendritic cells. D–F Flow cytometry and analysis of CD8 + T cells, TAMs and Tregs infiltration in tumor cells. *P < 0.05, **P < 0.01 and ***P < 0.001