Fig. 11From: Plasma exosome miRNA-26b-3p derived from idiopathic short stature impairs longitudinal bone growth via the AKAP2/ERK1/2 axismiR-26b-3p in exosomes can inhibit proliferation and endochondral ossification of growth plate chondrocytes via the AKAP2 axis in vivo. A–G The findings from western blotting, RT-qPCR, and immunohistochemistry revealed that AKAP2, which is the downstream target gene of miR-26b-3p, was significantly downregulated in growth plates. The data are presented as the mean ± SD. n = 3. Two groups were compared using T-test or three groups were compared using ANOVA followed by Tukey’s test. *P < 0.05, **P < 0.01, vs. controlBack to article page