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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Isoginkgetin-loaded reactive oxygen species scavenging nanoparticles ameliorate intervertebral disc degeneration via enhancing autophagy in nucleus pulposus cells

Fig. 6

Autophagy blocker reduces the anti-ECM degradation effect and anti-apoptotic effect of IGK@SeNP. A Western blotting analysis of the expression of autophagy-related proteins in NPCs induced by H2O2 with or without CQ (10 μM) for 24 h. B Densitometric analysis of autophagy-related protein levels. C Western blotting analysis of the expression of ECM metabolism-related proteins in NPCs induced by H2O2 with or without CQ (10 μM) for 24 h. D Densitometric analysis of ECM metabolism-related protein levels. E Western blotting analysis of the expression of apoptosis-related proteins in NPCs induced by H2O2 with or without CQ (10 μM) for 24 h. F Densitometric analysis of apoptosis-related protein levels. n = 3, mean ± SD. *p < 0.05 compared to the H2O2 group, †p < 0.05 compared to the IGK group, #p < 0.05 compared to the same treatment groups without CQ

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