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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: CaCO3 powder-mediated biomineralization of antigen nanosponges synergize with PD-1 blockade to potentiate anti-tumor immunity

Fig. 6

The ability of BANSs to inhibit tumor growth. (A) Schematic illustration of the therapeutic mechanism of BANSs. (B) Schematic illustration of BANSs study protocol. (C) Tumor growth curve. (D) Detection of intratumoral IFN-γ+CD8+ T cells by flow cytometry. (E) Detection of intratumoral Foxp3+CD4+ T cells by flow cytometry. (F) Detection of IFN-γ+CD8+ T cells in dLNs by flow cytometry. (G) Detection of IFN-γ+CD4+ T cells in dLNs by flow cytometry. Data are shown as the mean ± SD from four or five independent animals. (ns, not significant, *P < 0.05, **P < 0.01 and ***P < 0.001)

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