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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: CaCO3 powder-mediated biomineralization of antigen nanosponges synergize with PD-1 blockade to potentiate anti-tumor immunity

Fig. 7

Combination of BANS and αPD-1 for cancer immunotherapy. (A) Schematic illustration of BANSs in combination with the αPD-1 study protocol. (B) Survival curve of C57BL/6 mice. (C) Detection of activated T cells in LNs by flow cytometry (n = 4 to 6 mice per group). (D) Multiplex immunohistochemistry (mIHC) analysis of tumor immunosuppressive environment. (E) mIHC analysis of tumor immune environment. (ns, not significant, *P < 0.05, **P < 0.01, ***P < 0.001 and ****P < 0.0001)

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