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Table 1 Characterization of LR-loaded transfersome formulations

From: Lycorine transfersomes modified with cell-penetrating peptides for topical treatment of cutaneous squamous cell carcinoma

Formulation

Size (nm)

PDI

Zeta potential (mV)

EE (%)

LR@STFs

80.9 ± 3.6

0.151 ± 0.014

−20.9 ± 5.3

84.6 ± 2.5

LR@DTFs

77.6 ± 5.0

0.135 ± 0.017

 + 8.2 ± 3.4

86.0 ± 1.6

LR@STFs-CPP

98.0 ± 4.5 **

0.143 ± 0.022

 + 15.3 ± 2.3

89.5 ± 1.9

LR@DTFs-CPP

92.3 ± 2.7 #

0.128 ± 0.018

 + 38.4 ± 1.3

90.8 ± 1.2

  1. LR lycorine, STFs transfersomes with components of soybean phospholipid and sodium cholate hydrate, DTFs transfersomes with components of 1,2-dioleoyl-3-trimethylammonium-propane and sodium cholate hydrate, CPP cell-penetrating peptide, PDI polydispersity index, EE encapsulation efficiency
  2. **p < 0.01 when compared with LR@STFs
  3. #p < 0.05 when compared with LR@DTFs
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Journal of Nanobiotechnology

ISSN: 1477-3155

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