Fig. 3
Cumulative release of a Fe2+ and b GOX from HFNP@GOX@PFC after treatments with different concentrations of H2O2. c The self-produced H2O2 capability of HFNP@GOX@PFC nanosystem. d Time-dependent accumulation of H2O2 of HFNP@GOX@PFC after treatments with glucose for different times. e The self-amplificated generation of ·OH of PBS, HFNP, HFNP@GOX and HFNP@GOX@PFC with or without glucose. f Cytotoxicity of HC11 and 4T1 cells after treatment with HFNP@GOX@PFC at different doses of Fe2+ for 24 h. g Time-dependent cytotoxicity of 4T1 cells treated with PBS, GOX, PFC, HFNP, HFNP@GOX and HFNP@GOX@PFC for 24 h, 48 h and 72 h. h CLSM images and i fluorescence intensity of 4T1 cells after treated with PBS, FNP@GOX@PFC and HFNP@GOX@PFC for 12 h. Scale bar: 200 μm. Error bars present as mean ± SD (n = 6)