Fig. 5

Dynamics and bio-distribution of TMVP1-ICG-NPs. (A) Near infrared (NIR) fluorescence images of normal BALB/c mice at different times (0.5 h, 1 h, 2 h, 12 h, 24 h, 48 h) after the injection of TMVP1-ICG-NPs at a dose of 1.0 mg/kg. (B) Representative NIR fluorescence images of the main dissected organs at different time points after injection (H, heart; Li, liver; S, spleen; Lu, lung; K, kidney; I, intestine). (C) The mean NIR fluorescence signal intensity of the isolated organs was measured using the ROI tool.