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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: The application of extracellular vesicles in colorectal cancer metastasis and drug resistance: recent advances and trends

Fig. 4

EVs regulate metastasis and drug resistance in CRC. Molecular signaling pathways of metastasis and drug resistance, including PI3K, Akt, phosphatase and tensin homolog (PTEN), STAT3, programmed cell death 4 (PDCD4), Wnt, β-catenin, and suppressor of cytokine signaling 3 (SOCS3), are regulated by EVs. Induction of metastasis and drug resistance promotes CRC progression, and targeting EVs may impair CRC growth

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Journal of Nanobiotechnology

ISSN: 1477-3155

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